Chemical Immunology: Vol. 74 : CD14 in the Inflammatory Response
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Von Händler/Antiquariat, Anybook Ltd. [312675], Lincoln, United Kingdom.
Volume 74. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. In good all round condition. No dust jacket. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,600grams, ISBN:3805569173.

Von Händler/Antiquariat, The Book Exchange [3938380], Macclesfield, CHES, United Kingdom.
3805569173. Ex lib. hardcover. Appears unread. 226 pages, index, illustrated with photos, charts and diagrams. The adaptive immune system has the capacity to generate a large number of different antigen-specific receptors and hence can, in principle, provide defence against virtually any pathogen. However, there is a price to pay for this flexibility and sophistication, and that is that it takes several days to generate a protective response. In the meantime, the innate immune system must hold the infection at bay. The innate immune system requires receptors directed to structures which are commonly found in micro-organisms but which are not expressed in our own cells. One such structure is lipopolysaccharide (LPS), which is detected by our innate immune system because it possesses a high-affinity LPS receptor called CD14. This text underlines the importance of CD14 as a central component of the innate system. Issues examined include the structure-function relationships of CD14, the role of CD14 in cellular recognition of bacterial lipopolysaccharides, interactions of CD14 with components of gram-positive bacteria, soluble CD14-mediated cellular responses to LPS and non-inflammatory/anti-inflammatory CD14 responses. Contents clean, tight and bright.

Lieferung aus: Deutschland, Versandkostenfrei.
CD14 in the Inflammatory Response: In a world full of pathogens the ability to detect an incipient infection and to respond rapidly and appropriately to it is a decisive part of our survival strategy. The innate immune system provides the first response to an infection by initiating an inflammatory response and the monocyte surface molecule CD14 is a key element in this response system. The initial chapters in this volume describe the structure and ligand interactions of this important receptor molecule which is involved both in inflammation and in some aspects of apoptosis. The very recent results which illuminate the probable signal transduction pathways are also described. Overactivation of the inflammatory response can lead to systemic inflammation and septic shock. Attempts to intervene clinically in this system have been disappointing, and the reasons for these failures are discussed in the context of the expression of TNF which is upregulated by CD14. A discussion of new data on the clinical course of shock and the currently emerging therapeutic strategies rounds off the book. The information compiled in this well-edited volume will be of use to everyone working on problems of inflammation - a topic where fundamental research and clinical medicine meet. Clinicians will find the current state of scientific knowledge on the inflammatory response as induced via CD14 presented in a readable form, while the clinical aspects discussed will be of particular interest to scientists and students who lack a medical background. Englisch, Ebook.

Lieferung aus: Deutschland, E-Book zum Download.
In a world full of pathogens the ability to detect an incipient infection and to respond rapidly and appropriately to it is a decisive part of our survival strategy. The innate immune system provides the first response to an infection by initiating an inflammatory response and the monocyte surface molecule CD14 is a key element in this response system. The initial chapters in this volume describe the structure and ligand interactions of this important receptor molecule which is involved both in inflammation and in some aspects of apoptosis. The very recent results which illuminate the probable signal transduction pathways are also described. Overactivation of the inflammatory response can lead to systemic inflammation and septic shock. Attempts to intervene clinically in this system have been disappointing, and the reasons for these failures are discussed in the context of the expression of TNF which is upregulated by CD14. A discussion of new data on the clinical course of shock and the currently emerging therapeutic strategies rounds off the book. The information compiled in this well-edited volume will be of use to everyone working on problems of inflammation - a topic where fundamental research and clinical medicine meet. Clinicians will find the current state of scientific knowledge on the inflammatory response as induced via CD14 presented in a readable form, while the clinical aspects discussed will be of particular interest to scientists and students who lack a medical background.

Von Händler/Antiquariat, LowKeyBooks [65875000], Sumas, WA, U.S.A.
Books is in very good condition. Some creases from wear.

Von Händler/Antiquariat, Better World Books [51315977], Mishawaka, IN, U.S.A.
Former Library book. Great condition for a used book! Minimal wear.

Lieferung aus: Vereinigte Staaten von Amerika, Lagernd, zzgl. Versandkosten.
Hardcover book. 182 pages. Published by S. Karger AG (Switzerland).

Lieferung aus: Jordanien, Auf Lager. Versandkostenfrei. Tatsächliche Versandkosten können abweichen.
Von Händler/Antiquariat, Wadie Shop"We Deliver WORLDWIDE in 4 working days"
Karger, Freiburg i.B. Gebundene Ausgabe, Publiziert: 1999T, Produktgruppe: Book.