LTP mechanisms in the dentate gyrus in vivo: BDNF signaling, translation control, and gene function
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Von Händler/Antiquariat, BuySomeBooks [52360437], Las Vegas, NV, U.S.A.
Paperback. 132 pages. Dimensions: 8.4in. x 5.9in. x 0.5in.This book illustrates some of the various molecular mechanisms underlying synaptic plasticity in a subfield of the rat hippocampus called dentate gyrus (DG). Long-term potentiation (LTP) is a well- known model for studying strengthening of synaptic plasticity. In this study, LTP was induced in the DG by intrahippocampal infusion of brain-derived neurotrophic factor (BDNF-LTP). Alternatively, LTP was induced at medial perforant path-granule cell synapses by high frequency stimulation (HFS-LTP). The aim of the study was investigation of transcriptional and translational changes of activity-regulated cytoskeleton-associated protein (ArcArg3. 1) as well as changes in activation of the translation factors eIF4E (eukaryotic initiation factor 4E) and eEF2 (eukaryotic elongation factor-2) during LTP. We have demonstrated rapid activation of both translation factors and upregulation of Arc protein during BDNF-LTP. Additionally, an approach based on intrahippocampal infusion of Arc antisense oligodeoxynucleotides showed the importance of sustained Arc translation for the maintenance of both BDNF-LTP and HFS-LTP during a restricted time window. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN.

Von Händler/Antiquariat, AHA-BUCH GmbH [51283250], Einbeck, Germany.
This item is printed on demand - Print on Demand Titel. Neuware - This book illustrates some of the various molecular mechanisms underlying synaptic plasticity in a subfield of the rat hippocampus called dentate gyrus (DG). Long-term potentiation (LTP) is a well- known model for studying strengthening of synaptic plasticity. In this study, LTP was induced in the DG by intrahippocampal infusion of brain-derived neurotrophic factor (BDNF-LTP). Alternatively, LTP was induced at medial perforant path-granule cell synapses by high frequency stimulation (HFS-LTP). The aim of the study was investigation of transcriptional and translational changes of activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) as well as changes in activation of the translation factors eIF4E (eukaryotic initiation factor 4E) and eEF2 (eukaryotic elongation factor-2) during LTP. We have demonstrated rapid activation of both translation factors and upregulation of Arc protein during BDNF-LTP. Additionally, an approach based on intrahippocampal infusion of Arc antisense oligodeoxynucleotides showed the importance of sustained Arc translation for the maintenance of both BDNF-LTP and HFS-LTP during a restricted time window. 132 pp. Englisch.

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buecher.de GmbH & Co. KG, [1].
This book illustrates some of the various molecular mechanisms underlying synaptic plasticity in a subfield of the rat hippocampus called dentate gyrus (DG). Long-term potentiation (LTP) is a well-known model for studying strengthening of synaptic plasticity. In this study, LTP was induced in the DG by intrahippocampal infusion of brain-derived neurotrophic factor (BDNF-LTP). Alternatively, LTP was induced at medial perforant path-granule cell synapses by high frequency stimulation (HFS-LTP).The aim of the study was investigation of transcriptional and translational changes of activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) as well as changes in activation of the translation factors eIF4E (eukaryotic initiation factor 4E) and eEF2 (eukaryotic elongation factor-2) during LTP.We have demonstrated rapid activation of both translation factors and upregulation of Arc protein during BDNF-LTP. Additionally, an approach based on intrahippocampal infusion of Arc antisense oligodeoxynucleotides showed the importance of sustained Arc translation for the maintenance of both BDNF-LTP and HFS-LTP during a restricted time window.2009. 132 S.Versandfertig in 3-5 Tagen, Softcover.

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Von Händler/Antiquariat, super_star_seller.
This book illustrates some of the various molecular mechanisms underlying synaptic plasticity in a subfield of the rat hippocampus called dentate gyrus (DG). Long-term potentiation (LTP) is a well- known model for studying strengthening of synaptic plasticity. In this study, LTP was induced in the DG by intrahippocampal infusion of brain-derived neurotrophic factor (BDNF-LTP). Alternatively, LTP was induced at medial perforant path-granule cell synapses by high frequency stimulation (HFS-LTP). The aim of the study was investigation of transcriptional and translational changes of activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) as well as changes in activation of the translation factors eIF4E (eukaryotic initiation factor 4E) and eEF2 (eukaryotic elongation factor-2) during LTP. We have demonstrated rapid activation of both translation factors and upregulation of Arc protein during BDNF-LTP. Additionally, an approach based on intrahippocampal infusion of Arc antisense oligodeoxynucleotides showed the importance of sustained Arc translation for the maintenance of both BDNF-LTP and HFS-LTP during a restricted time window. Paperback, Label: VDM Verlag, VDM Verlag, Produktgruppe: Book, Publiziert: 2009-07-07, Studio: VDM Verlag, Verkaufsrang: 858797.

Von Händler/Antiquariat, English-Book-Service - A Fine Choice [1048135], Mannheim, Germany.
This item is printed on demand for shipment within 3 working days.