Semisynthesis and Bioactivities of Lichen Metabolites
5 Angebote vergleichen

Lichens are symbiotic of fungus and algae. Even though secondary metabolites of lichens are unique with respect to higher plants, they have received scarce attention as source of novel chemotypes. 14 compounds from 4 different lichens were isolated. Erythrin was successfully converted into its isomeric diphenyl ether via Smiles rearrangement. Oxidative coupling of diphenyl ether using palladium(II) acetate, lead to an efficient and unambiguous approach to dibenzofurans making it the first report on its semisynthesis via Smiles rearrangement. Isolated & semisynthesized compounds showed a wide range of biological activities includiig Zeorin with highest ?-glucosidase inhibitory activity (IC50 = 100.0 ± 0.3 µM), which is 7 times higher than of acarbose, (IC50 = 700.0 ± 10.4 µM) Divericatic, lecanoric, sekikaic, and lobaric acid showed significant antioxidant activity in SOI, with IC50 values being lower than the standard(propyl gallate) Orciniol & orsellenic acid showed 3-4 fold lower IC50 values when compared to standard thiourea in urease inhibitory assay. Compounds were also subjected to antimicrobial and toxicological assays. 0.501kg, 0.100/0.100/0.100.

Von Händler/Antiquariat, Books2Anywhere [190245], Fairford, GLOS, United Kingdom.
New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Von Händler/Antiquariat, Ria Christie Collections [59718070], Uxbridge, United Kingdom.
PRINT ON DEMAND Book; New; Publication Year 2017; Fast Shipping from the UK.

Lieferung aus: Vereinigte Staaten von Amerika, Auf Lager. Versandkostenfrei.
Von Händler/Antiquariat, Amazon Global Store US.
Scholars' Press, Taschenbuch, Publiziert: 2013-08-31T00:00:01Z, Produktgruppe: Book.

Lieferung aus: Vereinigte Staaten von Amerika, Lagernd, zzgl. Versandkosten.
Semisynthesis and Bioactivities of Lichen Metabolites,Vinitha Moolchand Thadhani.