Discovery and Optimization of New Anticancer Agents
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Bester Preis: € 44,33 (vom 25.10.2019)1
Discovery and Optimization of New Anticancer Agents
DE PB NW
ISBN: 9783639859683 bzw. 3639859685, in Deutsch, Scholar'S Press, Taschenbuch, neu.
Lieferung aus: Deutschland, Versandkostenfrei.
buecher.de GmbH & Co. KG, [1].
This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5).2015. 236 S. 220 mmVersandfertig in 3-5 Tagen, Softcover.
buecher.de GmbH & Co. KG, [1].
This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5).2015. 236 S. 220 mmVersandfertig in 3-5 Tagen, Softcover.
2
Discovery and Optimization of New Anticancer Agents (2015)
~EN PB NW
ISBN: 9783639859683 bzw. 3639859685, vermutlich in Englisch, Sps, Taschenbuch, neu.
Lieferung aus: Schweiz, Versandfertig innert 4 - 7 Werktagen.
Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors, This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5). Taschenbuch, 17.11.2015.
Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors, This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5). Taschenbuch, 17.11.2015.
3
Discovery and Optimization of New Anticancer Agents (2015)
~EN PB NW
ISBN: 9783639859683 bzw. 3639859685, vermutlich in Englisch, Sps, Taschenbuch, neu.
Lieferung aus: Österreich, zzgl. Versandkosten.
Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5). 17.11.2015, Taschenbuch.
Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5). 17.11.2015, Taschenbuch.
4
Discovery and Optimization of New Anticancer Agents
~EN NW AB
ISBN: 9783639859683 bzw. 3639859685, vermutlich in Englisch, VDM Verlag Dr. Müller, Saarbrücken, Deutschland, neu, Hörbuch.
Lieferung aus: Deutschland, Lieferzeit: 5 Tage.
This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5).
This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5).
5
Discovery and Optimization of New Anticancer Agents - Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors
~EN PB NW
ISBN: 9783639859683 bzw. 3639859685, vermutlich in Englisch, SPS, Taschenbuch, neu.
Lieferung aus: Deutschland, Versandkostenfrei.
Discovery and Optimization of New Anticancer Agents: This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5). Englisch, Taschenbuch.
Discovery and Optimization of New Anticancer Agents: This book is focused on molecular modeling using both structure based and ligand based design followed by synthesis of potential anticancer agents. Heat shock protein 90 and Cyclin dependent kinase 1 are used as a valid target for developing anticancer agents. Cyclin dependent kinase-1 (CDK1) and heat shock protein 90 (HSP90) were explored by molecular modeling towards the discovery of new dual inhibitors with potential anticancer properties. Both targets are critical for cancer progression and metastasis. In fact, CDK1 is considered as one of the natural substrates for HSP90, therefore, dual inhibition is expected to effectively arrest tumor growth, development and metastasis. The modeling studies were conducted employing structure-based (chapters 3, 4) and ligand-based methodologies (chapters 1, 2). Several new compounds were found to inhibit CDK1 (chapter 1) or HSP90, albeit selectively. Thiamine was found to possess good anti-HSP90 properties, and therefore was employed as lead for subsequent optimization of better HSP90 inhibitors based on pyridinium derivatives (chapter 5). Englisch, Taschenbuch.
6
Discovery and Optimization of New Anticancer Agents
~EN NW
ISBN: 3639859685 bzw. 9783639859683, vermutlich in Englisch, VDM Verlag Dr. Müller, Saarbrücken, Deutschland, neu.
Discovery and Optimization of New Anticancer Agents ab 58.9 EURO Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors.
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Discovery and Optimization of New Anticancer Agents: Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors (2015)
DE PB NW RP
ISBN: 9783639859683 bzw. 3639859685, in Deutsch, Scholars' Press, Taschenbuch, neu, Nachdruck.
Lieferung aus: Deutschland, Versandkostenfrei.
Von Händler/Antiquariat, English-Book-Service Mannheim [1048135], Mannheim, Germany.
This item is printed on demand for shipment within 3 working days.
Von Händler/Antiquariat, English-Book-Service Mannheim [1048135], Mannheim, Germany.
This item is printed on demand for shipment within 3 working days.
8
Symbolbild
Discovery and Optimization of New Anticancer Agents: Ligand Based and Structure Based Modeling of Heat Shock Protein 90 and Cyclin Dependent Kinase Inhibitors (2015)
DE PB NW
ISBN: 9783639859683 bzw. 3639859685, in Deutsch, Scholars' Press, Taschenbuch, neu.
Von Händler/Antiquariat, Irish Booksellers [57531671], Rumford, ME, U.S.A.
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