TOR and GSK3 in the ciliate Paramecium tetraurelia: Target of Rapamycin and Glycogen Synthase Kinase 3 pathway orthologs and their regulation of ciliary length/assembly
5 Angebote vergleichen
| Preise | 2013 | 2014 | 2015 |
|---|---|---|---|
| Schnitt | € 85,44 | € 85,43 | € 109,18 |
| Nachfrage |
1
TOR and GSK3 in the ciliate Paramecium tetraurelia Target of Rapamycin and Glycogen Synthase Kinase 3 pathway orthologs and their regulation of ciliary lengthassembly
DE PB NWISBN: 9783659128356 bzw. 365912835X, in Deutsch, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Von Händler/Antiquariat, BuySomeBooks [52360437], Las Vegas, NV, U.S.A.
Paperback. 340 pages. Dimensions: 8.7in. x 5.9in. x 0.8in.Target of rapamycin (TOR) is a serine threonine kinase that regulates cellular processes in response to the stresses and nutrients in the environment. We investigated TOR signaling pathway in the ciliate Paramecium tetraurelia (P. tetraurelia). Using BLAST (Basic Local Alignment Search Tool) we identified orthologs of the mammalian TOR, LST8, Akt, Rheb, Rag AB, Rag CD, SNAT2, Tap42, S6K, PKA and GSK3 in the P. tetraurelia. With RNA interference technique we established that depletion of these orthologs reduced cellular proliferation and arrested cells between G1 and S stages of the cell cycle. Furthermore, GSK3 depletion produced round looking cells with short, sparse cilia, and GSK3 was localized to the pellicle and cilia of P. tetraurelia. In addition to these investigations, we determined that inhibition of PKA with H89 prevented re-growth of cilia in de-ciliated cells. Our results possibly suggest that GSK3 and PKA work together in the regulation of ciliary length and or assembly in P. tetraurelia. We also hypothesize that these regulations are TOR dependent. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN.
Paperback. 340 pages. Dimensions: 8.7in. x 5.9in. x 0.8in.Target of rapamycin (TOR) is a serine threonine kinase that regulates cellular processes in response to the stresses and nutrients in the environment. We investigated TOR signaling pathway in the ciliate Paramecium tetraurelia (P. tetraurelia). Using BLAST (Basic Local Alignment Search Tool) we identified orthologs of the mammalian TOR, LST8, Akt, Rheb, Rag AB, Rag CD, SNAT2, Tap42, S6K, PKA and GSK3 in the P. tetraurelia. With RNA interference technique we established that depletion of these orthologs reduced cellular proliferation and arrested cells between G1 and S stages of the cell cycle. Furthermore, GSK3 depletion produced round looking cells with short, sparse cilia, and GSK3 was localized to the pellicle and cilia of P. tetraurelia. In addition to these investigations, we determined that inhibition of PKA with H89 prevented re-growth of cilia in de-ciliated cells. Our results possibly suggest that GSK3 and PKA work together in the regulation of ciliary length and or assembly in P. tetraurelia. We also hypothesize that these regulations are TOR dependent. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN.
2
Tor and Gsk3 in the Ciliate Paramecium Tetraurelia (Paperback) (2012)
DE PB NW RPISBN: 9783659128356 bzw. 365912835X, in Deutsch, LAP Lambert Academic Publishing, Germany, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, The Book Depository EURO [60485773], London, United Kingdom.
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
Die Beschreibung dieses Angebotes ist von geringer Qualität oder in einer Fremdsprache. Trotzdem anzeigen
3
Tor and Gsk3 in the Ciliate Paramecium Tetraurelia
DE PB NWISBN: 9783659128356 bzw. 365912835X, in Deutsch, LAP Lambert Academic Publishing, Taschenbuch, neu.
Von Händler/Antiquariat, THE SAINT BOOKSTORE [51194787], Southport, United Kingdom.
BRAND NEW PRINT ON DEMAND., Tor and Gsk3 in the Ciliate Paramecium Tetraurelia, Tatyana Svinkina.
BRAND NEW PRINT ON DEMAND., Tor and Gsk3 in the Ciliate Paramecium Tetraurelia, Tatyana Svinkina.
4
Tor and Gsk3 in the Ciliate Paramecium Tetraurelia (2014)
DE PB NWISBN: 9783659128356 bzw. 365912835X, in Deutsch, LAP LAMBERT ACADEMIC PUB 01/10/2014, Taschenbuch, neu.
Von Händler/Antiquariat, Paperbackshop-US [8408184], Secaucus, NJ, U.S.A.
New Book. This item is printed on demand. Shipped from US This item is printed on demand.
New Book. This item is printed on demand. Shipped from US This item is printed on demand.
5
TOR and GSK3 in the ciliate Paramecium tetraurelia: Target of Rapamycin and Glycogen Synthase Kinase 3 pathway orthologs and their regulation of ciliary length/assembly (2012)
DE PB NWISBN: 9783659128356 bzw. 365912835X, in Deutsch, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Von Händler/Antiquariat, ExtremelyReliable [8304062], RICHMOND, TX, U.S.A.
This item is printed on demand.
This item is printed on demand.
Lade…