Anticancer Properties of Novel Synthetic Vanillin Derivatives: The study of cytotoxicity, DNA binding and mutagenicity of (2-benzyloxy-3-methoxyphenyl) derivatives
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Anticancer Properties of Novel Synthetic Vanillin Derivatives
DE PB NWISBN: 9783659167713 bzw. 3659167711, in Deutsch, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
Von Händler/Antiquariat, BuySomeBooks [52360437], Las Vegas, NV, U.S.A.
Paperback. 164 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN.
Paperback. 164 pages. Dimensions: 8.7in. x 5.9in. x 0.4in.Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. This item ships from multiple locations. Your book may arrive from Roseburg,OR, La Vergne,TN.
2
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Anticancer Properties of Novel Synthetic Vanillin Derivatives (2012)
DE PB NW RPISBN: 9783659167713 bzw. 3659167711, in Deutsch, Lap Lambert Academic Publishing Aug 2012, Taschenbuch, neu, Nachdruck.
Von Händler/Antiquariat, AHA-BUCH GmbH [51283250], Einbeck, Germany.
This item is printed on demand - Print on Demand Titel. - Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. 164 pp. Englisch.
This item is printed on demand - Print on Demand Titel. - Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. 164 pp. Englisch.
3
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Anticancer Properties of Novel Synthetic Vanillin Derivatives (2014)
DE PB NWISBN: 9783659167713 bzw. 3659167711, in Deutsch, LAP LAMBERT ACADEMIC PUB 01/10/2014, Taschenbuch, neu.
Von Händler/Antiquariat, Paperbackshop-US [8408184], Secaucus, NJ, U.S.A.
New Book. This item is printed on demand. Shipped from US This item is printed on demand.
New Book. This item is printed on demand. Shipped from US This item is printed on demand.
4
Anticancer Properties of Novel Synthetic Vanillin Derivatives: The study of cytotoxicity, DNA binding and mutagenicity of (2-benzyloxy-3-methoxyphenyl) derivatives (2012)
EN PB NWISBN: 9783659167713 bzw. 3659167711, in Englisch, 164 Seiten, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
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Von Händler/Antiquariat, M + L.
Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. Paperback, Label: LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Product group: Book, Published: 2012-08-06, Studio: LAP LAMBERT Academic Publishing, Sales rank: 15061646.
Von Händler/Antiquariat, M + L.
Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. Paperback, Label: LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Product group: Book, Published: 2012-08-06, Studio: LAP LAMBERT Academic Publishing, Sales rank: 15061646.
5
Anticancer Properties of Novel Synthetic Vanillin Derivatives: The study of cytotoxicity, DNA binding and mutagenicity of (2-benzyloxy-3-methoxyphenyl) derivatives (2012)
EN PB USISBN: 9783659167713 bzw. 3659167711, in Englisch, 164 Seiten, LAP LAMBERT Academic Publishing, Taschenbuch, gebraucht.
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Lieferung aus: Vereinigte Staaten von Amerika, Usually ships in 1-2 business days, Real shipping costs can differ.
Von Händler/Antiquariat, super_star_seller.
Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. Paperback, Label: LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Product group: Book, Published: 2012-08-06, Studio: LAP LAMBERT Academic Publishing, Sales rank: 15061646.
Von Händler/Antiquariat, super_star_seller.
Benzyl-o-vanillin and benzimidazole nucleus serves as an important pharmacophore in drug discovery as it have a significant medicinal importance. Thus we explored the anticancer activity of three relative compounds and found their structure activity relationship compare with 2-benzyloxy-3-methoxybenzaldehyde main structure. According to the cytotoxicity analysis, they induce cell death of leukemic cell line through DNA fragmentation. DNA binding studies reveals that the DNA binding occurs through groove region. The higher mutagenicity might cause DNA mutation through interaction with the guanines while the lack of significant mutagenic activity suggests that the compound may target mainly the AT rich sequences of the nucleic acid. Hence, the present study provides a new insight of these novel (2-benzyloxy-3-methoxyphenyl) derivatives serving as a potential therapeutic agent against leukemia. This work should help shed some light on these exciting compounds and their SAR results, and should be especially useful to professionals in Oncology and cancer research feilds, or anyone else who may be considering utilizing DNA-drug interactions along with mutagenicity for research effort. Paperback, Label: LAP LAMBERT Academic Publishing, LAP LAMBERT Academic Publishing, Product group: Book, Published: 2012-08-06, Studio: LAP LAMBERT Academic Publishing, Sales rank: 15061646.
6
Anticancer Properties of Novel Synthetic Vanillin Derivatives: The study of cytotoxicity, DNA binding and mutagenicity of (2-benzyloxy-3-methoxyphenyl) derivatives (2012)
EN PB USISBN: 9783659167713 bzw. 3659167711, in Englisch, 164 Seiten, LAP LAMBERT Academic Publishing, Taschenbuch, gebraucht.
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Anticancer Properties of Novel Synthetic Vanillin Derivatives: The study of cytotoxicity, DNA binding and mutagenicity of (2-benzyloxy-3-methoxyphenyl) derivatives (2012)
EN PB NWISBN: 9783659167713 bzw. 3659167711, in Englisch, 164 Seiten, LAP LAMBERT Academic Publishing, Taschenbuch, neu.
New from: CDN$ 97.55 (9 Offers)
Used from: CDN$ 137.12 (2 Offers)
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Lieferung aus: Kanada, Usually ships within 1 - 2 business days, Real shipping costs can differ.
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Anticancer Properties of Novel Synthetic Vanillin Derivatives
~EN PB NWISBN: 9783659167713 bzw. 3659167711, vermutlich in Englisch, Taschenbuch, neu.
Von Händler/Antiquariat, European-Media-Service Mannheim [1048135], Mannheim, Germany.
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