Batch Effects and Noise in Microarray Experiments: Sources and Solutions
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Batch Effects and Noise in Microarray Experiments: InhaltsangabeList of Contributors.Foreword.Preface.1 Variation, Variability, Batches and Bias in Microarray Experiments: An Introduction (Andreas Scherer).2 Microarray Platforms and Aspects of Experimental Variation (John A Coller Jr).2.1 Introduction.2.2 Microarray Platforms.2.3 Experimental Considerations.2.4 Conclusions.3 Experimental Design (Peter Grass).3.1 Introduction.3.2 Principles of Experimental Design.3.3 Measures to Increase Precision and Accuracy.3.4 Systematic Errors in Microarray Studies.3.5 Conclusion.4 Batches and Blocks, Sample Pools and Subsamples in the Design and Analysis of Gene Expression Studies (Naomi Altman).4.1 Introduction.4.2 A Statistical Linear Mixed Effects Model for Microarray Experiments.4.3 Blocks and Batches.4.4 Reducing Batch Effects by Normalization and Statistical Adjustment.4.5 Sample Pooling and Sample Splitting.4.6 Pilot Experiments.4.7 Conclusions.Acknowledgements.5 Aspects of Technical Bias (Martin Schumacher, Frank Staedtler, Wendell D Jones, and Andreas Scherer).5.1 Introduction.5.2 Observational Studies.5.3 Conclusion.6 Bioinformatic Strategies for cDNA-Microarray Data Processing (Jessica Fahl&#233 n, Mattias Landfors, Eva Freyhult, Max Bylesj&#246 , Johan Trygg, Torgeir R Hvidsten, and Patrik Ryd&#233 n).6.1 Introduction.6.2 Pre-processing.6.3 Downstream Analysis.6.4 Conclusion.7 Batch Effect Estimation of Microarray Platforms with Analysis of Variance (Nysia I George and James J Chen).7.1 Introduction.7.2 Variance Component Analysis across Microarray Platforms.7.3 Methodology.7.4 Application: The MAQC Project.7.5 Discussion and Conclusion.Acknowledgements.8 Variance due to Smooth Bias in Rat Liver and Kidney Baseline Gene Expression in a Large Multi-laboratory Data Set (Michael J Boedigheimer, Jeff W Chou, J Chr, Englisch, Ebook.

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Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies. Наука, Образование/Прочая образовательная литература, book.

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Science, Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org , so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.

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Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized.Key Features:A thorough introduction to Batch Effects and Noise in Microrarray Experiments.A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data.An extensive overview of current standardization initiatives.All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced.An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies.

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"Batch Effects and Noise in Microarray Experiments: Sources and Solutions" looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies. Hardcover, Ausgabe: 1, Label: Wiley, Wiley, Produktgruppe: Book, Publiziert: 2009-12-14, Studio: Wiley, Verkaufsrang: 3722006.

Lieferung aus: Vereinigte Staaten von Amerika, Usually ships in 1-2 business days.
Von Händler/Antiquariat, DGBook.
"Batch Effects and Noise in Microarray Experiments: Sources and Solutions" looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whilst interpreting the relevant biological information. Each chapter focuses on sources of noise and batch effects before starting an experiment, with examples of statistical methods for detecting, measuring, and managing batch effects within and across datasets provided online. Throughout the book the importance of standardization and the value of standard operating procedures in the development of genomics biomarkers is emphasized. Key Features: A thorough introduction to Batch Effects and Noise in Microrarray Experiments. A unique compilation of review and research articles on handling of batch effects and technical and biological noise in microarray data. An extensive overview of current standardization initiatives. All datasets and methods used in the chapters, as well as colour images, are available on www.the-batch-effect-book.org, so that the data can be reproduced. An exciting compilation of state-of-the-art review chapters and latest research results, which will benefit all those involved in the planning, execution, and analysis of gene expression studies. Hardcover, Ausgabe: 1, Label: Wiley, Wiley, Produktgruppe: Book, Publiziert: 2009-12-14, Studio: Wiley, Verkaufsrang: 3722006.

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Batch Effects and Noise in Microarray Experiments ab 82.99 EURO Sources and Solutions, Batch Effects and Noise in Microarray Experiments ab 82.99 EURO Sources and Solutions.